Nodular histiocytic lymphoma: an aggressive nodular lymphoma with potential for prolonged disease-free survival
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Nodular histiocytic lymphoma: an aggressive nodular lymphoma with potential for prolonged disease-free survival.
Nodular histiocytic lymphoma (NH) is uncommon, and its natural history is not well defined. Of 473 patients with non-Hodgkin's lymphoma, we found 16 (3.4%) with NH. Most patients (13/16) presented with pathologic stage (PS) III or IV disease, including 7 with liver involvement. One patient (PS III) was initially treated with cyclophosphamide alone, and 4 patients received only radiotherapy, and...
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Lymphocyte-predominant Hodgkin's lymphoma (LPHL) differs in histologic and clinical presentation from classical Hodgkin's lymphoma (cHL). Treatment of LPHL patients using standard Hodgkin's lymphoma protocols leads to complete remission in more than 95% of patients. Survival and freedom from treatment failure are substantially worse in advanced-stage patients than for early-stage patients. Thus...
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In our experience, certain commonly cited immunophenotypic features of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) are not encountered in day-to-day practice. We reviewed 60 cases of NLPHL (18 women, 42 men; median age, 34 years) to discern immunophenotypic features from a large, single-institution cohort. All cases contained lymphocytic and histiocytic (L&H) cells. These cells expr...
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Ludmila Boudová, M. D., Emina Torlakovic, M. D., Jan Delabie, M.D., Peter Reimer, M.D., Beate Pfistner, Ph. D., Sabine Wiedenmann, M. D., Volker Diehl, M.D., Hans-Konrad Müller-Hermelink, M. D., Thomas Rüdiger, M. D. Department of Pathology, Charles University, Pilsen, Czech Republic, Department of Pathology, The Norwegian Radium Hospital, Oslo, Norway, 3 Medizinische Poliklinik, University of ...
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The evaluation of the results of CVP and MOPP chemotherapy in 80 patients with advanced stages of non-Hodgkin’s lymphoma indicates that 36 (45%) achieved a complete remission. Twenty-eight per cent of the entire group of patients remain free of disease for periods ranging from 4 mo to over 7 yr, with a projected median duration of complete remission of 3#{189} yr. Significant differences in pro...
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ژورنال
عنوان ژورنال: Blood
سال: 1980
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v56.1.98.98